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Single-Stranded Nucleic Acid Detection And Imaging System Using Cas9

Genome editing using CRISPR/Cas9 has enabled rapid and accessible alteration of specific genomic loci in many organisms. A flexible means to target nucleic acids would allow...

Hearing device that amplifies sound using a tympanostomy tube

Researchers at UC, Irvine have developed and improved a hearing aid apparatus for patients with moderate to severe hearing loss. This hearing aid device is comprised of a direct-DHD having a silicon mold on one end, the silicon having an attached...

Robust Genome Engineering in Primary Human T Cells using CRISPR/Cas9 Ribonu...

UCSF researchers have developed a powerful Cas9 RNP-based technology that uses purified Cas9 ribonucleoproteins (RNP) for successful and efficient genome editing in primary human CD4⁺ T cells. Cas9 protein pre-...

Immunomodulary Materials for Implantable Medical Devices

Traditional methods to reduce the foreign body response to biomaterials have focused on developing nonadhesive materials that prevent protein and cell binding. While this approach has had some success for materials administered into a fluid...

Methods for Selecting and Identifying Cancer Stem Cells

Cancer stem cells (CSC) have been identified in several types of cancer, including leukemia. While CSC are key to the progression of cancer and can be resistant to chemotherapeutic drugs, Leukemia...

Health Monitoring for the Heart and Aorta

Ballistocardiography (BCG) is a non-invasive measurement of the reaction of the whole body generated by the ejection of blood at each cardiac cycle. Consequently, it is an integration of multiple forces related to movements of blood inside the...

Method for Optimizing Health and Productivity of Milk Producing Animals

Most disease in dairy cows occurs during the transition period, which spans from about three weeks before calving to about one month after. Managing lactating dairy cows during this period is important because animals that perform well during...

MRI - Method for MRI Velocity Measurements and 4D Flow software

This invention is a novel technique for velocity measurements that combines CINE Phase Contrast MRI and balanced Steady State Free Precession.

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